Kontynuacja pytania "Interpretacja wyniku histopatologicznego" z 26 sierpnia 2016 r.
Oto caly report patologa:
Final diagnosis
1. Right sentinel lymph node #1
- 1 lump node(s) negative for carcinoma (H&E and cytokeratin immunostain on each block) (0/1)
Note : No definite treatment effect or biopsy site identified.
2. Right breast partial mastectomy;
- invasive ductal carcinoma
- size: 0.15 cm
- poorly differentiated
- margins: negative
distance to margins main specimen: 4mm to anterior, >5mm to all other margins (See Note) (See additional margins)
- Stage (AJCC7thEd): ypT1a NO(sn), at least Stage 1A
- biopsy site identified
- please see synoptic summary
Note: Tumor bed extends to the posterior margin. No tumor bed is identified in the additional margins.
3. Additional Posterior Margin Right:
- benign breast tissue
4. Additional Medial Margin Right:
- ductal hyperplasia
5. Interior Right
- benign breast tissue
6. Lateral Margin Right
- benign breast tissue
7. Superior Margin Right
- benign breast tissue
8. Anterior Margin Right
- benign fibroadipose tissue
Synoptic Summary
Malignant Neoplasm of the Breast
Procedure: Excision mastectomy
Laterality: Right
Lymph Node Sampling; Sentinel lymph node biopsy
Invasive Component:
Invasive Tumor Type: Invasive ductal carcinoma
Tumor Size: 0.15 cm
Histologic Grade(Nottingham): Grate 3 (score 8 or 9)
Glands/Tubules: Score 3 (<10% tumor forms glands/tubules)
Nuclear Pleomorphism: Score 3 (Prominent nucleoli, variability, bizarre)
Mitotic Rate: Too small to grade
Lymphovascular Invasion: Not identified
Surgical Margins(Invasive): Not identified
Distance to margins main specimen: 4mm to anterior, 5 mm to all other margins (see note)
Additional margins: Negative
Tumor Focality: Unifocal
Intraepithelial (in situ) Component
In Situ Tumor Type: No in situ tumor identified
Treatment Response:
Treatment Resp-Breast: Probable/definite response in invasive carcinoma
Treatment Resp-LNs: No metastasis or fibrous scarring
Staging:
Stage (AJCC 7th Ed): ypT1a NO(sn), at least Stage1A
Predictive/Prognostic Markers:
Performed on: Prior specimen: X16-478
Estrogen receptor(ER)status: Negative (<1%)
Progesterone receptor (PR) status: Negative (<1%)
Her2 (Imminohisochemistry): 1: Negative
Her2(FISH): Not amplified
Her2:CEP17 ratio: 1.2
Her2 copy number: 2.8
Note: Tumor bed extends to the posterior margin. No tumor bed is identified in additional margins.
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